Steroid-based hormones are able to move across cell membranes easily because they are water soluble

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I found a VERY informative website : – it explains the ‘wakening’ up of estrogen receptors very well – this is the simplified explanation : often estrogen receptors have down-regulated due to the presence of environmental estrogens – they are found everywhere and one has to try hard to avoid them. If one removes environmental estrogens from one’s environment the estrogen receptors become ‘normal’ again, and progesterone can be tolerated without experiencing nausea. Moreover less progesterone is required, because the environmental estrogens are gone! The many environmental estrogens – known as xenoestrogens (synthetic), or phytoestrogens(plant based) include most cleaning materials, lotions, soaps, shampoos, laundry materials and most things fragrant…. use a basic unperfumed simple soap for hair and washing, even for dishes, and for cleaning use vinegar/water mix and baking soda… It has worked for me.

Crush, guillotine and avulsion mechanisms are three of the most common forms of traumatic amputation. Crush injuries are the most common and can result in significant tissue damage and injury. Because of the injury associated with crush mechanisms, amputations resulting from these forces are less likely to be successfully reattached. In contrast, guillotine injuries involve sharp edges, resulting in less tissue disruption. As a result, body parts that are amputated by guillotine forces are likely to have better reattachment and recovery outcomes.

[ Editor's Note: Chryste Gaines, MBA, Olympic gold and bronze medal sprinter and former teammate of Marion Jones in the 2000 Sydney Olympic Games, stated the following in a Dec. 22, 2008 email to in response to the IOC ruling:

"We are being unfairly punished. If the drug testing agencies cannot determine if an athlete is taking performance enhancing drugs how are the teammates supposed to know?... It negates all the family functions, church functions, and social events we missed in the name of winning an Olympic medal." ]

During minor illness (., flu or fever >38° C [° F]) the hydrocortisone dose should be doubled for 2 or 3 days. The inability to ingest hydrocortisone tablets warrants parenteral administration. Most patients can be educated to self administer hydrocortisone, 100 mg IM, and reduce the risk of an emergency room visit. Hydrocortisone, 75 mg/day, provides adequate glucocorticoid coverage for outpatient surgery. Parenteral hydrocortisone, 150 to 200 mg/day (in three or four divided doses), is needed for major surgery, with a rapid taper to normal replacement during the recovery. Patients taking more than 100 mg hydrocortisone/day do not need any additional mineralocorticoid replacement. All patients should wear some form of identification indicating their adrenal insufficiency status.

Steroid-based hormones are able to move across cell membranes easily because they are water soluble

steroid-based hormones are able to move across cell membranes easily because they are water soluble

During minor illness (., flu or fever >38° C [° F]) the hydrocortisone dose should be doubled for 2 or 3 days. The inability to ingest hydrocortisone tablets warrants parenteral administration. Most patients can be educated to self administer hydrocortisone, 100 mg IM, and reduce the risk of an emergency room visit. Hydrocortisone, 75 mg/day, provides adequate glucocorticoid coverage for outpatient surgery. Parenteral hydrocortisone, 150 to 200 mg/day (in three or four divided doses), is needed for major surgery, with a rapid taper to normal replacement during the recovery. Patients taking more than 100 mg hydrocortisone/day do not need any additional mineralocorticoid replacement. All patients should wear some form of identification indicating their adrenal insufficiency status.

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