Diagnosis Index entries containing back-references to B59 :
HIV: Responding to an Emerging Challenge (National Network of STD/HIV Prevention Program and such as free voluntary and
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Stomatitis is the most commonly reported adverse reaction in patients treated with Afinitor (see sections and ). In a post-marketing single-arm study in postmenopausal women with advanced breast cancer (N=92), topical treatment with dexamethasone mg/5 ml alcohol-free oral solution was administered as a mouthwash (4 times daily for the initial 8 weeks of treatment) to patients at the time of initiating treatment with Afinitor (10 mg/day) plus exemestane (25 mg/day) to reduce the incidence and severity of stomatitis. The incidence of Grade ≥2 stomatitis at 8 weeks was % (n=2/85 evaluable patients) which was lower than historically reported. The incidence of Grade 1 stomatitis was % (n=16/85) and no cases of Grade 3 or 4 stomatitis were reported. The overall safety profile in this study was consistent with that established for everolimus in the oncology and tuberous sclerosis complex (TSC) settings, with the exception of a slightly increased frequency of oral candidiasis which was reported in % (n=2/92) of patients.