Inhaled corticosteroids copd risk pneumonia

Given that the substantial escalation in inhaled glucocorticoid therapy prevented exacerbations in adults (the STICS trial did not show any benefit in children), the main question arising from this trial is whether such high doses warrant use as an exacerbation-prevention strategy. Main concerns are not only the local toxic effects of inhaled glucocorticoids but also the adrenal suppression from the quadruple dose. Even if this quadruple dosing was promoted by the national guidelines, numerous studies have found that only about 25% of . patients (children and adults) fill prescriptions for inhaled corticosteroids. Therefore, an additional question is whether patients will use such dosing. 

Inhaled corticosteroids are medications used to treat asthma. They are taken by using an inhaler. This medication should be taken consistently so that it decreases inflammation in the airways of your lungs and prevents asthma flare-ups. Inhaled corticosteroids are considered the most effective long term usage medication for control and management of asthma. Depending upon the severity of your asthma, your physician may combine an inhaled corticosteroid with a long-acting beta-2 agonist to treat your condition. Oral and intravenous corticosteroids may be required for acute asthma flare-ups or for severe symptoms.

There is some evidence that sun exposure can accelerate steroid-induced skin atrophy, the development of which can be limited by protecting the skin, particularly the face and arms, from the sun.  Daily use of a broad-spectrum sunscreen (UVB and UVA block) and appropriate protective clothing is recommended. 10 , 12 - 14   Patients on corticosteroids should also be encouraged to regularly use moisturisers on their arms and legs, as these may reduce bruising and tearing of the skin from minor trauma. 11   Evidence suggests that topical tretinoin can increase the epidermal thickness of sun-damaged atrophic skin, but long-term use may be necessary. 14   In dermatological practice, topical retinoids are used to help reverse skin atrophy caused by sun exposure or corticosteroid use.

"Rick’s growth and bone development have been affected by his high steroid use.   He was evaluated completely in the Pediatric Endocrinology clinic at the children’s hospital.   Their findings indicate Rick is constitutionally delayed in growth and his severe asthma and requirements for high-dose steroids over the past several years have contributed to this delay.   Based on their information, Rick has an estimated adult height of 5 feet 6 inches. Rick also has steroid induced osteoporosis that needs to be dealt with.  "

Inhaled corticosteroids copd risk pneumonia

inhaled corticosteroids copd risk pneumonia

"Rick’s growth and bone development have been affected by his high steroid use.   He was evaluated completely in the Pediatric Endocrinology clinic at the children’s hospital.   Their findings indicate Rick is constitutionally delayed in growth and his severe asthma and requirements for high-dose steroids over the past several years have contributed to this delay.   Based on their information, Rick has an estimated adult height of 5 feet 6 inches. Rick also has steroid induced osteoporosis that needs to be dealt with.  "

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